Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP53 genetic alterations in head-and-neck carcinomas from Brazil.

International journal of cancer - 30 Mar 1998

Nagai M A, Miracca E C, Yamamoto L, Moura R P, Simpson A J, Kowalski L P, Brentani R R

Abstract excerpt

In this study we investigated the incidence of mutations and loss of heterozygosity (LOH) of the TP53 gene in DNA samples from paired tumor and adjacent normal tissue from 90 patients with untreated squamous-cell carcinoma of the head and neck. Evidence for TP53 mutations were demonstrated in 53% (48/90) of the cases analyzed. All cases were also examined for loss of heterozygosity, using a PCR-based polymorphic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Carcinoma, Squamous Cell
Share to Frameshift Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Loss of Heterozygosity

Share to Mutation

Share to Sequence Deletion

Share to Smoking

Source

Identifiers

PMID: 9533755
DOI: 10.1002/(sici)1097-0215(19980330)76:1<13::aid-ijc3>3.0.co;2-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP53 genetic alterations in head-and-neck carcinomas from Brazil.PMID 9533755Read ↗

TP53 mutations in head and neck cancer.Semantic proximity Read ↗

TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response.Semantic proximity Read ↗

p53 in head and neck cancer: Functional consequences and environmental implications of TP53mutationsSemantic proximity Read ↗

Characterization of p53 gene mutations in a Brazilian population with oral squamous cell carcinomas.Semantic proximity Read ↗

TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selectionSemantic proximity Read ↗

[Analysis of mutations within the TP53 gene in patients with squamous cell carcinoma of the head and neck].Semantic proximity Read ↗

TP53 and head and neck neoplasms.Semantic proximity Read ↗

Profile of TP53 gene mutations in sinonasal cancer.Semantic proximity Read ↗

Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers.Semantic proximity Read ↗

Mutational Status of CDKN2A and TP53 Genes in Laryngeal Squamous Cell Carcinoma.Semantic proximity Read ↗

p53 mutations in human head and neck cancer cell lines.Semantic proximity Read ↗

The spectrum of mutations in TP53 in laryngeal cancer patients from a high-incidence population shows similarities to many of the known mutational hotspots.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.