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Article

Targeted next-generation sequencing of TP53 in oral tongue carcinoma from non-smokers.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 17 Sept 2016

Faden Daniel L, Arron Sarah T, Heaton Chase M, DeRisi Joseph, South Andrew P, Wang Steven J

Abstract excerpt

BACKGROUND: Little is known regarding the etiology and genomic underpinnings of Oral Tongue Squamous Cell Carcinoma (OTSCC) in patients who lack traditional risk factors, yet the incidence is increasing. In particular, the rate, and role, of TP53 mutations in this cohort has been heavily debated in the literature. METHODS: Tumor DNA from forty-three non-smokers with OTSCC underwent next generation sequencing of...

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Source

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Identifiers

PMID: 27640185
DOI: 10.1186/s40463-016-0160-4
PMCID: PMC5027093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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