T cell development in mice lacking all T cell receptor zeta family members (Zeta, eta, and FcepsilonRIgamma).

doi:10.1084/jem.187.7.1093

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Article

T cell development in mice lacking all T cell receptor zeta family members (Zeta, eta, and FcepsilonRIgamma).

The Journal of experimental medicine - 6 Apr 1998

Shores E W, Ono M, Kawabe T, Sommers C L, Tran T, Lui K, Udey M C, Ravetch J, Love P E

Abstract excerpt

The zeta family includes zeta, eta, and FcepsilonRIgamma (Fcgamma). Dimers of the zeta family proteins function as signal transducing subunits of the T cell antigen receptor (TCR), the pre-TCR, and a subset of Fc receptors. In mice lacking zeta/eta chains, T cell development is impaired, yet low...

Topics

Animals
Antigens, CD
Cells, Cultured
Cytokines
Dimerization
Flow Cytometry
Gene Expression Regulation, Developmental
Interferon-gamma
Lymph Nodes
Mice
Mice, Knockout
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptors, Antigen, T-Cell

Signal Transduction

Spleen

T-Lymphocytes

Thymus Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 9529325
DOI: 10.1084/jem.187.7.1093
PMCID: PMC2212212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9529325-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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