Article
Modulation of Sp1 Phosphorylation by Human Immunodeficiency Virus Type 1 Tat
1 Apr 1998
Abstract excerpt
We previously reported (K. T. Jeang, R. Chun, N. H. Lin, A. Gatignol, C. G. Glabe, and H. Fan, J. Virol. 67: 6224-6233, 1993) that human immunodeficiency virus type 1 (HIV-1) Tat and Sp1 form a protein-protein complex. Here, we have characterized the physical interaction and a functional consequence of Tat-Sp1 contact. Using in vitro protein chromatography, we mapped the region in Tat that contacts Sp1 to amino...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
