Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cooperative Interaction between HIV-1 Regulatory Proteins Tat and Vpr Modulates Transcription of the Viral Genome

1 Nov 2000

Abstract excerpt

The virion-associated protein of human immunodeficiency virus, type 1 (HIV-1), Vpr, is a small protein with 96 amino acid residues that has the ability to modulate transcription of HIV-1 long terminal repeat (LTR) promoter activity and affects several cellular functions. In this study we have employed molecular approaches to further investigate the mechanism by which Vpr exerts its regulatory effect upon the LTR....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10931842
DOI: 10.1074/jbc.m005197200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cooperative Interaction between HIV-1 Regulatory Proteins Tat and Vpr Modulates Transcription of the Viral GenomePMID 10931842Read ↗

The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB.Semantic proximity Read ↗

HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1Semantic proximity Read ↗

Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to TranscriptionSemantic proximity Read ↗

Tat is a multifunctional viral protein that modulates cellular gene expression and functionsSemantic proximity Read ↗

Effect of HIV-1 Vpr on Cell Cycle RegulatorsSemantic proximity Read ↗

HIV-1 Regulatory/Accessory Genes: Keys to Unraveling Viral and Host Cell BiologySemantic proximity Read ↗

Human immunodeficiency virus vpr product is a virion-associated regulatory protein.Semantic proximity Read ↗

HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV TherapiesSemantic proximity Read ↗

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription.Semantic proximity Read ↗

Transdominant activity of human immunodeficiency virus type 1 Vpr with a mutation at residue R73.Semantic proximity Read ↗

Human immunodeficiency virus type 1 Vpr: functions and molecular interactionsSemantic proximity Read ↗

Characterization of a Human TAR RNA-Binding Protein That Activates the HIV-1 LTRSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.