Article
Parvovirus H-1 P38 promoter requires the trans-activation region (tar), an SP1 site, and a TATA box for full activity.
Virology - 1 Mar 1992
Gu M L, Chen F X, Rhode S L
Abstract excerpt
In the parvovirus H-1 P38 promoter, there are sequences identified as a TATA box, an SP1 site, and a trans-activation responsive element (tar). It was previously shown that the parvovirus H-1 nonstructural protein NS1 positively regulates the expression of the P38 promoter for the viral capsid protein gene via the tar. To characterize the tar element further, a series of single-point mutations of the tar was...
Topics
- Base Sequence
- Capsid
- DNA Mutational Analysis
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Parvoviridae
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid
- Sp1 Transcription Factor