Article
Analysis of potential phosphorylation sites in human T cell leukemia virus type 1 Tax.
Journal of biomedical science - 1 Jan 2000
Krause Boehm A, Stawhecker J A, Semmes O J, Jankowski P E, Lewis R, Hinrichs S H
Abstract excerpt
The human T cell leukemia virus type 1 (HTLV-1) Tax is a phosphoprotein, however, the contribution of phosphorylation to Tax activity is unknown. Previous studies have shown that phosphorylation of Tax occurs on serine residue(s), within one tryptic fragment, in response to 4beta-phorbol-12beta-myristate-13alpha-acetate, in both mouse and human cells. Studies were conducted in multiple cell lines to identify the...
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