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Article

Carbamyl-phosphate synthetase domain of the yeast multifunctional protein Ura2 is necessary for aspartate transcarbamylase inhibition by UTP.

FEBS letters - 30 Jan 1998

Antonelli R, Estevez L, Denis-Duphil M

Abstract excerpt

In Saccharomyces cerevisiae, the first two reactions of pyrimidine biosynthesis are catalyzed by the multifunctional protein Ura2 carrying both carbamyl-phosphate synthetase (CPSase) and aspartate transcarbamylase (ATCase) enzyme activities. In order to study how UTP regulates both of these activ...

Topics

Aspartate Carbamoyltransferase
Binding Sites
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
Green Fluorescent Proteins
Kinetics
Luminescent Proteins
Multienzyme Complexes
Phenotype
Pyrimidines
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uridine Triphosphate

Source

Identifiers

PMID: 9489999
DOI: 10.1016/s0014-5793(98)00010-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9489999-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Carbamyl-phosphate synthetase domain of the yeast multifunctional protein Ura2 is necessary for aspartate transcarbamylase inhibition by UTP.PMID 9489999Read ↗

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