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Article

Genetic evidence that promoter P2 is the physiologically significant promoter for the pyrBI operon of Escherichia coli K-12.

Journal of bacteriology - 1 Apr 1993

Liu C, Donahue J P, Heath L S, Turnbough C L

Abstract excerpt

The pyrBI operon of Escherichia coli K-12 encodes the two nonidentical subunits of the pyrimidine biosynthetic enzyme aspartate transcarbamylase (ATCase). Expression of this operon is negatively regulated by pyrimidine availability primarily through UTP-sensitive transcriptional attenuation and, to a lesser extent, at the level of transcriptional initiation. Previous studies indicated that the pyrBI operon was...

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Identifiers

PMID: 8468295
DOI: 10.1128/jb.175.8.2363-2369.1993
PMCID: PMC204525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Genetic evidence that promoter P2 is the physiologically significant promoter for the pyrBI operon of Escherichia coli K-12.PMID 8468295Read ↗

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Biochemical strategy of the genome as expressed in regulation of pyrimidine metabolism.Semantic proximity Read ↗

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