Article
Modulation of HTLV-I gene expression by HIV-1 Rev through an alternative RxRE-independent pathway mediated by the RU5 portion of the 5'-LTR.
Biochemical and biophysical research communications - 4 Feb 1998
Kubota S, Furuta R A, Hatanaka M, Pomerantz R J
Abstract excerpt
The 5'-RU5 portion of human T-lymphocyte virus type I (HTLV-I) long terminal repeat (LTR) had been reported to contain cis-acting elements for the controlled viral gene expression by the rex gene product. In this study, the human immunodeficiency virus type I (HIV-1) Rev protein was found to enha...
Topics
- Animals
- Base Sequence
- COS Cells
- Chromosome Mapping
- Gene Expression Regulation, Viral
- Gene Products, rev
- Gene Products, rex
- Genes, env
- HIV-1
- HeLa Cells
- Human T-lymphotropic virus 1
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Messenger
- RNA, Viral
- Repetitive Sequences, Nucleic Acid