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Article

Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation.

PLoS pathogens - 1 Apr 2007

Brandt Sabine, Blissenbach Maik, Grewe Bastian, Konietzny Rebecca, Grunwald Thomas, Uberla Klaus

Abstract excerpt

The main function attributed to the Rev proteins of immunodeficiency viruses is the shuttling of viral RNAs containing the Rev responsive element (RRE) via the CRM-1 export pathway from the nucleus to the cytoplasm. This restricts expression of structural proteins to the late phase of the lentiviral replication cycle. Using Rev-independent gag-pol expression plasmids of HIV-1 and simian immunodeficiency virus and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17432934
DOI: 10.1371/journal.ppat.0030054
PMCID: PMC1851978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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