Article
Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein.
Journal of virology - 1 Aug 1990
Felber B K, Drysdale C M, Pavlakis G N
Abstract excerpt
Rev is an essential regulatory protein of the human immunodeficiency virus type 1 (HIV-1) that affects the transport and half-life of certain viral mRNAs. Rev exerts its function via a unique element, the Rev-responsive element (RRE), located within the env region of HIV-1. It has been previously...
Topics
- Base Sequence
- Feedback
- Gene Expression Regulation, Viral
- Gene Products, rev
- HIV-1
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Plasmids
- Proviruses
- RNA Splicing
- RNA, Messenger
- RNA, Viral
- Trans-Activators
- Transfection
- rev Gene Products, Human Immunodeficiency Virus