Article
Characterization of a Dictyostelium factor that acts synergistically with DIF to induce terminal stalk cell differentiation.
Developmental biology - 15 Apr 1997
Yamada Y, Okamoto K, Williams J
Abstract excerpt
The differentiation of Dictyostelium prestalk cells is induced by the chlorinated hexaphenone DIF-1 and their maturation into stalk cells at culmination occurs by activation of the cAMP-dependent protein kinase (PKA). Medium harvested from developing Dictyostelium cells will act synergistically w...
Topics
- 8-Bromo Cyclic Adenosine Monophosphate
- Animals
- Cell Differentiation
- Cells, Cultured
- Chromatography, High Pressure Liquid
- Culture Media, Conditioned
- Cyclic AMP-Dependent Protein Kinases
- Dictyostelium
- Enzyme Activation
- Extracellular Matrix Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Reporter
- Hexanones
- Molecular Weight
- Mutation
- Protozoan Proteins
- Signal Transduction