Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of alphavirus 26S mRNA transcription by replicase component nsP2.

1 Feb 1998

Abstract excerpt

Semliki Forest virus (SFV) mutant ts4 has a reversible temperature-sensitive defect in the synthesis the subgenomic 26S mRNA. The viral nonstructural protein nsP2 was identified as a regulator of 26S synthesis by transferring nsP2 coding sequences from ts4 into the infectious SFV cDNA clone (SFoto) to create SFots4. Sequencing identified the causal mutation as C4038U, predicting the amino acid change M781T in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to interferon and immune responses
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9472615
DOI: 10.1099/0022-1317-79-2-309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of alphavirus 26S mRNA transcription by replicase component nsP2.PMID 9472615Read ↗

Enzymatic defects of the nsP2 proteins of Semliki Forest virus temperature-sensitive mutants.Semantic proximity Read ↗

Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a nonstructural protein, nsP4.Semantic proximity Read ↗

Alphavirus minus-strand RNA synthesis: identification of a role for Arg183 of the nsP4 polymerase.Semantic proximity Read ↗

Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.Semantic proximity Read ↗

Regulation of Semliki Forest virus RNA replication: a model for the control of alphavirus pathogenesis in invertebrate hosts.Semantic proximity Read ↗

Ribosomal Protein S6 Associates with Alphavirus Nonstructural Protein 2 and Mediates Expression from Alphavirus MessagesSemantic proximity Read ↗

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis.Semantic proximity Read ↗

Suppressor mutations that allow sindbis virus RNA polymerase to function with nonaromatic amino acids at the N-terminus: evidence for interaction between nsP1 and nsP4 in minus-strand RNA synthesis.Semantic proximity Read ↗

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR.Semantic proximity Read ↗

Transactivation of programmed ribosomal frameshifting by a viral proteinSemantic proximity Read ↗

Regulation of the sequential processing of Semliki Forest virus replicase polyprotein.Semantic proximity Read ↗

An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.