Article
Analysis of human immunodeficiency virus type 1 (HIV-1) variants and levels of infection in dendritic and T cells from symptomatic HIV-1-infected patients.
The Journal of general virology - 1 Feb 1998
Patterson S, English N R, Longhurst H, Balfe P, Helbert M, Pinching A J, Knight S C
Abstract excerpt
Dendritic cells (DC) are required to initiate primary cellular immune responses. Human immunodeficiency virus type 1 (HIV-1) infection of DC may be central to transmission and persistence of virus and in the pathogenesis of AIDS. In symptomatic HIV-1-infected patients the proportion of DC in the...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- DNA Primers
- Dendritic Cells
- Evolution, Molecular
- Flow Cytometry
- Gene Products, env
- Genetic Variation
- HIV-1
- Humans
- Molecular Sequence Data
