Article
Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection.
Journal of acquired immune deficiency syndromes (1999) - 1 May 2008
Dillon Stephanie M, Robertson Kathryn B, Pan Samuel C, Mawhinney Samantha, Meditz Amie L, Folkvord Joy M, Connick Elizabeth, McCarter Martin D, Wilson Cara C
Abstract excerpt
Dendritic cells (DCs) from HIV-1-infected individuals display numeric and functional defects, and recent evidence suggests that HIV-1 can directly and indirectly activate DCs in vitro. The in vivo activation state and compartmentalization of DC subsets during HIV-1 infection remain poorly understood, however. We evaluated phenotypic and functional characteristics of myeloid dendritic cells (mDCs) and plasmacytoid...
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