Article
Infection frequency of dendritic cells and CD4+ T lymphocytes in spleens of human immunodeficiency virus-positive patients.
Journal of virology - 1 Aug 1995
McIlroy D, Autran B, Cheynier R, Wain-Hobson S, Clauvel J P, Oksenhendler E, Debré P, Hosmalin A
Abstract excerpt
Dendritic cells (DC) are specialized antigen-presenting leukocytes that are responsible for the activation of naive as well as memory T lymphocytes. If infected by human immunodeficiency virus (HIV), DC may transfer virus to CD4+ lymphocytes. However, the question of whether DC are infected in vivo is controversial. As HIV infection is more active in secondary lymphoid organs than in blood, infection of splenic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
