Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and functional analysis of CD1a+ dendritic cells from cats chronically infected with feline immunodeficiency virus.

Comparative immunology, microbiology and infectious diseases - 1 Oct 2015

Zhang Lin, Reckling Stacie, Dean Gregg A

Abstract excerpt

Numerous studies suggest dendritic cell (DC) dysfunction is central to the dysregulated immune response during HIV infection; however, in vivo studies are lacking. In the present study we used feline immunodeficiency virus (FIV) infection of cats as a model for HIV-1 infection to assess the maturation and function of dendritic cells, in vivo and in vitro. We compared CD1a+ DC migration, surface phenotype,...

Topics

Animals
Antigen Presentation
Antigens, CD1
Cats
Cell Movement
Chronic Disease
Dendritic Cells
Disease Models, Animal
Feline Acquired Immunodeficiency Syndrome
HIV Infections
Immunodeficiency Virus, Feline

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymph Nodes

Lymphocyte Activation

Lymphocyte Culture Test, Mixed

Phenotype

T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 26385493
DOI: 10.1016/j.cimid.2015.07.003
PMCID: PMC10252145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and functional analysis of CD1a+ dendritic cells from cats chronically infected with feline immunodeficiency virus.PMID 26385493Read ↗

Dendritic cells in viral pathogenesis: protective or defective?Semantic proximity Read ↗

A Morbillivirus Infection Shifts DC Maturation Toward a Tolerogenic Phenotype to Suppress T Cell Activation.Semantic proximity Read ↗

Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection.Semantic proximity Read ↗

Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirsSemantic proximity Read ↗

FIV infection induces unique changes in phenotype and cellularity in the medial iliac lymph node and intestinal IEL.Semantic proximity Read ↗

Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype.Semantic proximity Read ↗

Changes in dendritic cell migration and activation during SIV infection suggest a role in initial viral spread and eventual immunosuppression.Semantic proximity Read ↗

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells.Semantic proximity Read ↗

Murine respiratory tract dendritic cells: isolation, phenotyping and functional studies.Semantic proximity Read ↗

Follicular dendritic cell contributions to HIV pathogenesis.Semantic proximity Read ↗

Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis.Semantic proximity Read ↗

Phenotypic changes in CD8+ peripheral blood lymphocytes in cats infected with feline immunodeficiency virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.