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Article

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells.

Journal of virology - 1 Aug 2002

Sanders Rogier W, de Jong Esther C, Baldwin Christopher E, Schuitemaker Joost H N, Kapsenberg Martien L, Berkhout Ben

Abstract excerpt

Dendritic cells (DC) support human immunodeficiency virus type 1 (HIV-1) transmission by capture of the virus particle in the mucosa and subsequent transport to the draining lymph node, where HIV-1 is presented to CD4(+) Th cells. Virus transmission involves a high-affinity interaction between the DC-specific surface molecule DC-SIGN and the viral envelope glycoprotein gp120 and subsequent internalization of the...

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Identifiers

PMID: 12097593
DOI: 10.1128/jvi.76.15.7812-7821.2002
PMCID: PMC136398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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