Article
Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair.
Nucleic acids research - 15 Feb 1998
Shen M R, Zdzienicka M Z, Mohrenweiser H, Thompson L H, Thelen M P
Abstract excerpt
The molecular basis for the DNA repair dysfunction observed in mutant Chinese hamster ovary cell lines of X-ray repair cross complementing group 1 (XRCC1) is unknown and the exact role of the XRCC1 protein remains unclear. To help clarify the role of the XRCC1 gene we analyzed four mutant cell lines of this complementation group and a revertant cell line for XRCC1 protein content and for sequence alterations in...
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