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Article

ATM dysfunction in Chinese hamster XRCC8 mutants.

Biochemical and biophysical research communications - 3 Dec 2024

Chailapakul Piyawan, Maeda Junko, Kato Takamitsu A

Abstract excerpt

XRCC8 is a member of the X-ray cross-complementing (XRCC) family, whose responsible gene has not been identified. Previous studies suggested ATM and other genes were potential candidates for XRCC8, but this was not confirmed. In this study, we characterized three V79-derived XRCC8 mutant cells: V-C4, V-E5, and V-G8. Western blot analysis showed reduced expression of the ATM protein in three XRCC8 mutants, and...

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PMID: 39142236
DOI: 10.1016/j.bbrc.2024.150491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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