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Article

DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.

Biochemistry - 1 Nov 2005

Wong Heng-Kuan, Kim Daemyung, Hogue Barbara A, McNeill Daniel R, Wilson David M

Abstract excerpt

Base excision repair (BER) is the major corrective pathway for most spontaneous, oxidative, and alkylation DNA base and sugar damage. X-ray cross-complementing 1 (XRCC1) has been suggested to function at nearly every step of this repair process, primarily through direct protein-protein interactions. Using whole cell extract (WCE) repair assays and DNA damage measurement techniques, we examined systematically the...

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Identifiers

PMID: 16245950
DOI: 10.1021/bi051161o

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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