Article
The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA.
Nucleic acids research - 15 Feb 1998
Drotschmann K, Aronshtam A, Fritz H J, Marinus M G
Abstract excerpt
Vsr DNA mismatch endonuclease is the key enzyme of very short patch (VSP) DNA mismatch repair and nicks the T-containing strand at the site of a T-G mismatch in a sequence-dependent manner. MutS is part of the mutHLS repair system and binds to diverse mismatches in DNA. The function of the mutL gene product is currently unclear but mutations in the gene abolish mutHLS -dependent repair. The absence of MutL...
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