Article
Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus.
Journal of bacteriology - 1 May 2005
Prunier Anne-Laure, Leclercq Roland
Abstract excerpt
The mutator phenotype has been linked in several bacterial genera to a defect in the methyl-mismatch repair system, in which the major components are MutS and MutL. This system is involved both in mismatch repair and in prevention of recombination between homeologous fragments in Escherichia coli and has been shown to play an important role in the adaptation of bacterial populations in changing and stressful...
Topics
- Adenosine Triphosphatases
- Bacterial Proteins
- Cloning, Molecular
- DNA Repair Enzymes
- DNA-Binding Proteins
- Escherichia coli Proteins
- MutS DNA Mismatch-Binding Protein
- Mutation
- Operon
- Phenotype
- Recombination, Genetic
- Staphylococcus aureus
