Article
Further support for linkage of extreme obesity to the obese gene in a study group of obese children and adolescents.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 1997
Roth H, Hinney A, Ziegler A, Barth N, Gerber G, Stein K, Brömel T, Mayer H, Siegfried W, Schäfer H, Remschmidt H, Grzeschik K H, Hebebrand J
Abstract excerpt
The role of the obese gene in human obesity is presently unclear. Evidence for linkage of markers flanking the gene to obesity has been found in some but not all studies. We investigated transmission disequilibrium between two highly polymorphic microsatellite markers (D7S504 and D7S1875) flanking the human obese gene (OB) and extreme obesity in a study group of German children and adolescents. Due to the early...
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