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Article

Linkage and linkage disequilibrium mapping of genes influencing human obesity in chromosome region 7q22.1-7q35.

Diabetes - 1 Jun 2003

Li Wei-Dong, Li Ding, Wang Shuang, Zhang Shuanglin, Zhao Hongyu, Price R Arlen

Abstract excerpt

Linkage results suggest that the region of chromosome 7 containing the leptin gene cosegregates with extreme obesity; however, leptin coding region mutations are rare. To investigate whether the leptin flanking sequence and/or a larger 40-cM region (7q22.1-7q35) contributes to obesity, we genotyped individuals from 200 European American families segregating extreme obesity and normal weight (1,020 subjects) using...

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PMID: 12765970
DOI: 10.2337/diabetes.52.6.1557

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NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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