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Article

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.

PloS one - 26 Dec 2007

Hinney Anke, Nguyen Thuy Trang, Scherag André, Friedel Susann, Brönner Günter, Müller Timo Dirk, Grallert Harald, Illig Thomas, Wichmann H-Erich, Rief Winfried, Schäfer Helmut, Hebebrand Johannes

Abstract excerpt

BACKGROUND: Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood. We have performed a genome wide association study (GWA) for early onset (extreme) obesity. METHODOLOGY/PRINCIPAL FINDINGS: a) GWA (Genome-Wide Human SNP Array 5.0 comprising 440,794 single nucleotide polymorphisms) for early onset extreme obesity based on...

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Identifiers

PMID: 18159244
DOI: 10.1371/journal.pone.0001361
PMCID: PMC2137937

Genes

FTO

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.PMID 18159244Read ↗

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