Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Practical considerations on the use of extreme sib-pairs for obesity.

Methods of information in medicine - 1 Jan 2006

Ziegler A, Barth N, Coners H, Mayer H, Hebebrand J

Abstract excerpt

OBJECTIVES: The extreme sib-pair approach has been shown to be a powerful strategy to identify susceptibility loci linked to quantitative traits. The body mass index is the usually assessed trait in genetic studies on human obesity. Environmental factors clearly play an important role for this trait. We hypothesized that the low weight of most sibs who were seemingly discordant to the obese index proband was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Confounding Factors, Epidemiologic
Share to Feeding Behavior

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germany

Share to Mass Screening

Share to Siblings

Share to Social Environment

Share to Surveys and Questionnaires

Source

Identifiers

PMID: 16964359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Practical considerations on the use of extreme sib-pairs for obesity.PMID 16964359Read ↗

Obesity related phenotypes in families selected for extreme obesity and leanness.Semantic proximity Read ↗

Maternal transmission bias of inherited genetic variants in severe early-onset obesitySemantic proximity Read ↗

[Genetic Analyses of Complex Phenotypes Through the Example of Anorexia Nervosa and Bodyweight Regulation].Semantic proximity Read ↗

Binge-eating disorder as a distinct familial phenotype in obese individuals.Semantic proximity Read ↗

Assortative mating for obesity.Semantic proximity Read ↗

Association of etiological factors across the extreme end and continuous variation in disordered eating in female Swedish twins.Semantic proximity Read ↗

Individual-specific risk factors for anorexia nervosa: a pilot study using a discordant sister-pair design.Semantic proximity Read ↗

Absence of linkage between human obesity and the mouse agouti homologous region (20q11.2) or other markers spanning chromosome 20q.Semantic proximity Read ↗

Further support for linkage of extreme obesity to the obese gene in a study group of obese children and adolescents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.