Article
Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene.
Molecular psychiatry - 1 Sept 1996
Comings D E, Gade R, MacMurray J P, Muhleman D, Peters W R
Abstract excerpt
To examine the possible role of genetic variants of the OB gene in obesity we examined alleles of a dinucleotide repeat polymorphism, D7S1875, close to the gene, in a group of adult, non-Hispanic Caucasians. There was a significant correlation with body mass index (BMI) at age 26-30 years for mal...
Topics
- Adult
- Aged
- Alleles
- Analysis of Variance
- Body Mass Index
- Compulsive Behavior
- Depression
- Feeding Behavior
- Female
- Genetic Variation
- Genotype
- Homozygote
- Humans
- Male
- Middle Aged
- Obesity
- Polymorphism, Genetic
- Receptors, Dopamine D2