A new family of genes which, when mutated, suppress the inhibitory effect of the mod(mdg4)1u1 mutation on y2 expression in Drosophila melanogaster.

doi:10.1007/s004380050626

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Article

A new family of genes which, when mutated, suppress the inhibitory effect of the mod(mdg4)1u1 mutation on y2 expression in Drosophila melanogaster.

Molecular & general genetics : MGG - 1 Dec 1997

Bezborodova E, Kulikov A, Georgiev P

Abstract excerpt

The suppressor of Hairy-wing [su(Hw)] protein inhibits the function of transcriptional enhancers located distal to the promoter with respect to the location of su(Hw)-binding sites (insulation). Mutations in the modifier of mdg4 [mod(mdg4)] interfere with insulation and enhance the effect of the...

Topics

Animals
Drosophila Proteins
Drosophila melanogaster
Female
Genes, Insect
Genes, Suppressor
Male
Mutation
Transcription Factors

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