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Article

Interaction between mutations in the suppressor of Hairy wing and modifier of mdg4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations.

Genetics - 1 Feb 1996

Georgiev P, Kozycina M

Abstract excerpt

The suppressor of Hairy-wing [su(Hw)] protein mediates the mutagenic effect of the gypsy retrotransposon by repressing the function of transcriptional enhancers located distally from the promoter with respect to the position of the su(Hw)-binding region. Mutations in a second gene, modifier of mdg4, also affect the gypsy-induced phenotype. Two major effects of the mod(mdg4)1u1 mutation can be distinguished: the...

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Identifiers

PMID: 8852842
DOI: 10.1093/genetics/142.2.425
PMCID: PMC1206977

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction between mutations in the suppressor of Hairy wing and modifier of mdg4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations.PMID 8852842Read ↗

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[Genetic analysis of the interaction of mutations in two genes, controlling expression of MDG4].Semantic proximity Read ↗

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Characterization of functional domains of the su(Hw) protein that mediate the silencing effect of mod(mdg4) mutations.Semantic proximity Read ↗

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The DNA-binding and enhancer-blocking domains of the Drosophila suppressor of Hairy-wing protein.Semantic proximity Read ↗

The suppressor of Hairy-wing binding region is required for gypsy mutagenesis.Semantic proximity Read ↗

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