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Article

Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.

Genetics - 1 Jul 2005

Golovnin Anton, Melnick Elena, Mazur Alexander, Georgiev Pavel

Abstract excerpt

The insulator element from the gypsy transposon is a DNA sequence that blocks activation of a promoter by a transcriptional enhancer when placed between them. The insulator contains reiterated binding sites for the Suppressor of Hairy-wing [Su(Hw)] zinc-finger protein. A protein encoded by another gene, modifier of mdg4 [mod(mdg4)], is also required for the enhancer-blocking activity of the Su(Hw) insulator. Here...

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Identifiers

PMID: 15520254
DOI: 10.1534/genetics.104.034587
PMCID: PMC1451172

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Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.PMID 15520254Read ↗

Characterization of functional domains of the su(Hw) protein that mediate the silencing effect of mod(mdg4) mutations.Semantic proximity Read ↗

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The gypsy insulator of Drosophila affects chromatin structure in a directional manner.Semantic proximity Read ↗

EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.Semantic proximity Read ↗

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