Article
Joint segregation and linkage analysis of a quantitative trait compared to separate analyses.
Genetic epidemiology - 1 Jan 1997
Gauderman W J, Faucett C L, Morrison J L, Carpenter C L
Abstract excerpt
Our goal was to determine the degree to which joint segregation and linkage analysis leads to increased efficiency for estimating the recombination fraction and to greater power for detecting linkage, compared to separate analyses. We concentrated on the quantitative phenotype Q2 and analyzed linkage with a tightly linked marker, a loosely linked marker, and eight unlinked markers, the latter chosen to evaluate...
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