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Article

Type I error rates in association versus joint linkage/association tests in related individuals.

Genetic epidemiology - 1 Feb 2007

Kent Jack W, Dyer Thomas D, Göring Harald H H, Blangero John

Abstract excerpt

Positional gene discovery on pedigree data typically involves initial gross localization by linkage analysis with subsequent finer localization by association analysis in areas that show evidence of linkage. We examine the effect of including linkage information when testing for association in the context of variance-components-based pedigree analysis. We present simulation experiments showing that, at least in...

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PMID: 17219375
DOI: 10.1002/gepi.20200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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