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Article

HLA binding characteristics and generation of cytotoxic lymphocytes against peptides derived from oncogenic proteins.

Tumori - 1 Jan 2000

Bertazzoli C, Marchesi E, Dermime S, Ravagnani F, Parmiani G, Gambacorti-Passerini C

Abstract excerpt

AIMS AND BACKGROUND: Structurally altered proteins (derived from chromosomal translocations or gene mutations) can be considered tumor specific antigens and represent an attractive target for a T-cell mediated response. T lymphocytes recognize antigens in the form of peptides bound to HLA-molecules. MATERIALS AND METHODS: Peptides derived from oncogenic proteins were screened for the presence of HLA binding...

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PMID: 9428921

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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