Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Class I MHC-peptide interaction: structural and functional aspects.

Behring Institute Mitteilungen - 1 Jul 1994

Ruppert J, Kubo R T, Sidney J, Grey H M, Sette A

Abstract excerpt

The structural requirements for the interaction between antigens and class I molecules was investigated through the use of a quantitative assay to measure peptide binding to different MHC class I alleles. We determined the permissiveness of the main anchors reported by Rammensee and his group for peptide binding and defined an extended motif for peptides binding to the HLA-A2.1 allele, including the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Binding Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Molecular Sequence Data

Share to Peptides

Share to Structure-Activity Relationship

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 7998914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Class I MHC-peptide interaction: structural and functional aspects.PMID 7998914Read ↗

Class I MHC-peptide interactions: structural requirements and functional implications.Semantic proximity Read ↗

Peptide binding motifs for MHC class I and II molecules.Semantic proximity Read ↗

Identification of T-cell epitopes using allele-specific ligand motifs.Semantic proximity Read ↗

Analysis of the structure of naturally processed peptides bound by class I and class II major histocompatibility complex molecules.Semantic proximity Read ↗

Pocketcheck: updating the HLA class I peptide specificity roadmap.Semantic proximity Read ↗

Structural properties of MHC class II ligands, implications for the prediction of MHC class II epitopes.Semantic proximity Read ↗

Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules.Semantic proximity Read ↗

MHC class I-peptide interactions and TCR recognition.Semantic proximity Read ↗

Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.Semantic proximity Read ↗

In silico analysis of peptide binding features of HLA-B*4006.Semantic proximity Read ↗

Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population.Semantic proximity Read ↗

Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.