Article
HLA-G peptide preferences change in transformed cells: impact on the binding motif.
Immunogenetics - 1 Aug 2018
Celik Alexander A, Simper Gwendolin S, Hiemisch Wiebke, Blasczyk Rainer, Bade-Döding Christina
Abstract excerpt
HLA-G is known for its strictly restricted tissue distribution. HLA-G expression could be detected in immune privileged organs and many tumor entities such as leukemia, multiple myeloma, and non-Hodgkin and Hodgkin's lymphoma. This functional variability from mediation of immune tolerance to facilitation of tumor immune evasion strategies might translate to a differential NK cell inhibition between...
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