Article
HLA-A0201 and HLA-B7 binding peptides in the EBV-encoded EBNA-1, EBNA-2 and BZLF-1 proteins detected in the MHC class I stabilization assay. Low proportion of binding motifs for several HLA class I alleles in EBNA-1.
International immunology - 1 Apr 1995
Stuber G, Dillner J, Modrow S, Wolf H, Székely L, Klein G, Klein E
Abstract excerpt
B lymphocytes immortalized with EBV in vitro, lymphoblastoid cell lines (LCL), express eight EBV-encoded proteins, EBV nuclear antigens -1 to -6 (EBNA-1 to -6), and latent membrane proteins 1 and 2 (LMP 1 and 2). After appropriate stimulations of blood lymphocytes from seropositive individuals, M...
Topics
- Alleles
- Amino Acid Sequence
- Antigens, Viral
- DNA-Binding Proteins
- Epstein-Barr Virus Nuclear Antigens
- HLA-A Antigens
- HLA-B7 Antigen
- Herpesvirus 4, Human
- Humans
- Molecular Sequence Data
- Protein Binding
- Trans-Activators
- Viral Proteins