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Article

Induction in transgenic mice of HLA-A2.1-restricted cytotoxic T cells specific for a peptide sequence from a mutated p21ras protein.

Clinical and experimental immunology - 1 May 1999

Escobar P, Yu Z, Terskikh A, Holmes N, Corradin G, Mach J P, Healy F

Abstract excerpt

Cytotoxic T cells (CTL) recognize short peptides that are derived from the proteolysis of endogenous cellular proteins and presented on the cell surface as a complex with MHC class I molecules. CTL can recognize single amino acid substitutions in proteins, including those involved in malignant transformation. The mutated sequence of an oncogene may be presented on the cell surface as a peptide, and thus...

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Source

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Identifiers

PMID: 10337009
DOI: 10.1046/j.1365-2249.1999.00873.x
PMCID: PMC1905280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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