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Article

Mother-daughter precursor cell fate transformation after Cdc2 down-regulation in the Drosophila bristle lineage.

Developmental biology - 15 Dec 2004

Fichelson Pierre, Gho Michel

Abstract excerpt

The Drosophila bristle lineage is an excellent system in which to study how cell cycle and fate determination are synchronized in invariant cell lineages. In this model, five different cells arise from a single precursor cell, pI, after four asymmetric cell divisions. Cell diversity is achieved by the asymmetric segregation of cell determinants, such as Numb and Neuralized (Neur), resulting in differential...

Topics

Animals
CDC2 Protein Kinase
Cell Cycle
Cell Lineage
Down-Regulation
Drosophila Proteins
Drosophila melanogaster
Neurons
Phenotype
Recombinant Fusion Proteins
Stem Cells

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PMID: 15581871
DOI: 10.1016/j.ydbio.2004.08.043

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