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Article

Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits.

The Journal of biological chemistry - 9 Jan 1998

Snyder P M, Cheng C, Prince L S, Rogers J C, Welsh M J

Abstract excerpt

Members of the DEG/ENaC protein family form ion channels with diverse functions. DEG/ENaC subunits associate as hetero- and homomultimers to generate channels; however the stoichiometry of these complexes is unknown. To determine the subunit stoichiometry of the human epithelial Na+ channel (hENaC), we expressed the three wild-type hENaC subunits (alpha, beta, and gamma) with subunits containing mutations that...

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Identifiers

PMID: 9422716
DOI: 10.1074/jbc.273.2.681

Genes

BNC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits.PMID 9422716Read ↗

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Asymmetric Pendrin Homodimer Reveals its Molecular Mechanism as Anion ExchangerSemantic proximity Read ↗

A region directly following the second transmembrane domain in gamma ENaC is required for normal channel gating.Semantic proximity Read ↗

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