Article
A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones.
Proceedings of the National Academy of Sciences of the United States of America - 6 Sept 2005
Lin Heping, Mann Kevin J, Starostina Elena, Kinser Ronald D, Pikielny Claudio W
Abstract excerpt
Odorants and pheromones as well as sweet- and bitter-tasting small molecules are perceived through activation of G protein-coupled chemosensory receptors. In contrast, gustatory detection of salty and sour tastes may involve direct gating of sodium channels of the DEG/ENaC family by sodium and hydrogen ions, respectively. We have found that ppk25, a Drosophila melanogaster gene encoding a DEG/ENaC channel...
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