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Article

Determination of epithelial Na+ channel subunit stoichiometry from single-channel conductances.

The Journal of general physiology - 1 Jul 2007

Anantharam Arun, Palmer Lawrence G

Abstract excerpt

The epithelial Na(+) channel (ENaC) is a multimeric membrane protein consisting of three subunits, alpha, beta, and gamma. The total number of subunits per functional channel complex has been described variously to follow either a tetrameric arrangement of 2alpha:1beta:1gamma or a higher-ordered stoichiometry of 3alpha:3beta:3gamma. Therefore, while it is clear that all three ENaC subunits are required for full...

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Identifiers

PMID: 17562820
DOI: 10.1085/jgp.200609716
PMCID: PMC2154365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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