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Article

A region directly following the second transmembrane domain in gamma ENaC is required for normal channel gating.

The Journal of biological chemistry - 17 Oct 2003

Booth Rachell E, Tong Qiusheng, Medina Jorge, Snyder Peter M, Patel Pravina, Stockand James D

Abstract excerpt

We used a yeast one-hybrid complementation screen to identify regions within the cytosolic tails of the mouse alpha, beta, and gamma epithelial Na+ channel (ENaC) important to protein-protein and/or protein-lipid interactions at the plasma membrane. The cytosolic COOH terminus of alphaENaC contained a strongly interactive domain just distal to the second transmembrane region (TM2) between Met610 and Val632....

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Identifiers

PMID: 12897071
DOI: 10.1074/jbc.M305400200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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