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Article

The bile acid-sensitive ion channel (BASIC), the ignored cousin of ASICs and ENaC

23 Dec 2013

Abstract excerpt

The DEG/ENaC gene family of ion channels is characterized by a high degree of structural similarity and an equally high degree of diversity concerning the physiological function. In humans and rodents, the DEG/ENaC family comprises 2 main subgroups: the subunits of the epithelial Na(+) channel (ENaC) and the subunits of the acid sensing ion channels (ASICs). The bile acid-sensitive channel (BASIC), previously...

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PMID: 24365967
DOI: 10.4161/chan.27493

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