Article
Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes.
Development (Cambridge, England) - 1 Sept 1998
Griffin K J, Amacher S L, Kimmel C B, Kimelman D
Abstract excerpt
Inhibition of fibroblast growth factor (FGF) signaling prevents trunk and tail formation in Xenopus and zebrafish embryos. While the T-box transcription factor Brachyury (called No Tail in zebrafish) is a key mediator of FGF signaling in the notochord and tail, the pathways activated by FGF in non-notochordal trunk mesoderm have been uncertain. Previous studies have shown that the spadetail gene is required for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
