Article
Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes.
Development (Cambridge, England) - 1 Sept 1998
Griffin K J, Amacher S L, Kimmel C B, Kimelman D
Abstract excerpt
Inhibition of fibroblast growth factor (FGF) signaling prevents trunk and tail formation in Xenopus and zebrafish embryos. While the T-box transcription factor Brachyury (called No Tail in zebrafish) is a key mediator of FGF signaling in the notochord and tail, the pathways activated by FGF in no...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Primers
- DNA-Binding Proteins
- Fetal Proteins
- Fibroblast Growth Factors
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Mesoderm
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Phenotype
- Polymerase Chain Reaction
- Sequence Homology, Amino Acid
- Signal Transduction