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Article

The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine.

European journal of clinical pharmacology - 1 Jan 1997

Hasselström J, Yue Q Y, Säwe J

Abstract excerpt

METHODS: Codeine (50 mg) was administered to 12 extensive metabolisers (EM) and 12 poor metabolisers (PM) of debrisoquine. The oro-caecal transit time was estimated by the hydrogen breath test. The urinary excretion of codeine and metabolites during a 6-h interval was estimated after simultaneous analysis of codeine, morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), morphine (M), normorphine (NM),...

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Identifiers

PMID: 9403287
DOI: 10.1007/s002280050353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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