Article
Expression of Tetrahymena histone H4 in yeast.
Biochimica et biophysica acta - 1 Nov 1997
Fogel G B, Brunk C F
Abstract excerpt
Histone H4 is one of the most conserved proteins known. The very low rate of nonsynonymous substitution in H4 suggests that it fulfills an essential function in virtually all eukaryotes. While the majority of histone H4 sequences differ only slightly from the general consensus H4 sequence, yeast and Tetrahymena sequences diverge substantially from both the consensus and from each other. This study demonstrates...
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