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Article

Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Nov 2005

Hyland Edel M, Cosgrove Michael S, Molina Henrik, Wang Dongxia, Pandey Akhilesh, Cottee Robert J, Boeke Jef D

Abstract excerpt

The biological significance of recently described modifiable residues in the globular core of the bovine nucleosome remains elusive. We have mapped these modification sites onto the Saccharomyces cerevisiae histones and used a genetic approach to probe their potential roles both in heterochromatic regions of the genome and in the DNA repair response. By mutating these residues to mimic their modified and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16260619
DOI: 10.1128/MCB.25.22.10060-10070.2005
PMCID: PMC1280264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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