Article
The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression.
Molecular and cellular biology - 1 Aug 1991
Morgan B A, Mittman B A, Smith M M
Abstract excerpt
The N-terminal domains of the histones H3 and H4 are highly conserved throughout evolution. Mutant alleles deleted for these N-terminal domains were constructed in vitro and examined for function in vivo in Saccharomyces cerevisiae. Cells containing a single deletion allele of either histone H3 o...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Biological Evolution
- Cell Cycle
- Cloning, Molecular
- Escherichia coli
- Histones
- Kinetics
- Molecular Sequence Data
- Plasmids
- Polymerase Chain Reaction
- Restriction Mapping
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid