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Article

The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression.

Molecular and cellular biology - 1 Aug 1991

Morgan B A, Mittman B A, Smith M M

Abstract excerpt

The N-terminal domains of the histones H3 and H4 are highly conserved throughout evolution. Mutant alleles deleted for these N-terminal domains were constructed in vitro and examined for function in vivo in Saccharomyces cerevisiae. Cells containing a single deletion allele of either histone H3 or histone H4 were viable. Deletion of the N-terminal domain of histone H4 caused cells to become sterile and...

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Identifiers

PMID: 2072911
DOI: 10.1128/mcb.11.8.4111-4120.1991
PMCID: PMC361224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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